摘要
采用配比的方法,以原发性肝癌、肝硬化、慢性乙型肝炎和非肝病病人为研究对象,检测其HBV感染6项血清学标志。结果表明,原发性肝癌、肝硬化、慢性肝炎的HBV感染总阳性率分别为98.21%,93.75%和96.43%;与对照组有显著差异;3组的感染标志组合较一致,HBsAg和抗-HBc双阳性为主;HBeAg在肝硬化和慢性肝炎中明显高于肝癌组;抗-HBe和抗-HBcIgM3组间无显著差别。提示HBV感染的慢性化与原发性肝癌病因有密切联系。
In an attempt to clarify the relationship between HBV in-
fection and hepatocellular carcinoma,we have studied the HBV infection
serum marks in 448 patients suffering from hepatocellular carcinoma
(PHC),chronic hepatitis B(CHB),liver cirrhosis(LC)and non-liver di-
seases(NLD).The incidence of HBV infection serum marks were res-
pectively 98.21% in PHC,96.43% in CHB and 93.75% in LC,signifi-
cantly higher than that in controls,The major combination of serum marks
was HBsAg and anti-HBC among liver disease patients,The incidence
for anti-HBe and anti-HBcIgM were no significant difference among
the three liver disease groups,but HBeAg was significantly higher in
CHB and in LC.The result indicated HBV infection was closely associ-
ated with PHC.
出处
《山东医科大学学报》
1989年第3期45-47,共3页
Acta Academiae Medicinae Shandong
关键词
肝肿瘤
肝硬变
原发性
乙型肝炎
Hepatitis B virus
Liver neoplasms
Liver cirrhosis
Hepatitis B
Serum Marks
