摘要
支气管哮喘90例,随机分为特布他林组46例(男26例,女20例;年龄30±s 13a)及氨茶碱组44例(男23例,女21例;年龄31±14a)。剂量:特布他林1.25-2.5mg,tid po×3wk;氨茶碱0.1g,tid,po×3wk。结果:特布他林组总有效率76％,1s用力呼气量(FEV_1)改善率占64％(26/41);氨茶碱组则相应为77％(34/44)、65％(26/40);P>0.05。不良反应少。
Terbutaline was given to 46 patierus(M 26, F 20; age 30±.s 13 a)with bronchial asthma. The initial close was 1.25 mg, po, tid, for 1 wk and then 2.5 mg, tid,po, for 2 wk. To serve as a control, aminophylline was given to the other 44 patients(M 23, F 21; age 31 ± 14 a)with the same asthma, the dose was 0.1 g, tid, po for 3 wk. Results showed both efficacies were similar. In the terbutaline group, the total response rate was 76%(35/46), and the forced expiratory volume in one second (FEV1) was improved 64%(26/41);while that of aminophylline group were 77%(34/44)and 65%(26/40)respectively. Adverse effects of the 2 groups were mild.
出处
《新药与临床》
CSCD
北大核心
1993年第2期80-81,共2页
关键词
特布他林
治疗应用
氨茶碱
哮喘
terbutaline/therapeutic use
aminophylline/therapeutic use
asthma/drug therapy
forced expiratory volume
