摘要
研究目的探讨不同剂量肾上腺素的应用在心肺脑复苏中的临床疗效。研究背景肾上腺素治疗成人心脏停搏的常规剂量为每分钟0.5～1mg。近年来越来越多的研究证明心脏停搏行心肺复苏所需的肾上腺素剂量大于目前常规剂量。研究方法对63例心脏停搏患者应用不同剂量肾上腺素,分常规剂量组、大剂量组和超大剂量组。观察自主心律、心率、血压、呼吸恢复情况、心电变化。对自身循环恢复病例行血生化监测。研究结果大剂量组的自主心律、血压和自身循环的恢复及心肺复苏成功率较常规剂量组为优。超大剂量组临床效应与常规剂量组类似,但毒副作用表现突出。结论心肺脑复苏中应用大剂量肾上腺素(5mg/分),可提高复苏成功率及存活率。
Objective To research for the effects of‘different does adrenaline on the cardio—pulmonaryand cerebral resuscitation and observe it's side:el'-fects,we performed this study. Background The routine dose of adl。enalinetreating the adult heart arrest is 0.5～1 mg/’rain.Recently,toOl。e and more experimental studiespl’oved that adrenaline adapted dose COlne back tolire or conscjousness while heart arrest is morethan routine dose. Methods The difierent dose ot’adrenalinefor 63 patients was divided into three group:rou—tine dose group,large dose group and over largedose gl’oup.Their heart rhythm themselves,heartrate.blood pressure,respiratory recovery and theclectrocardjograln we!’e obsel ved 1’he bloodbiochemistry indexes of'patients recovering theblood circulation themselves were monitored. Resuits The effect ol large dose gl’oup Wasbetter than the routine dose in the recovel’Y ol、heart rhythm themselves and cardio——puimonary——cerebral resuscItation.The clinical effect of OVerhirge dose group was similar to the rontine dosegroup.bu t die formei‘’s toxicity and side—effectswas much gi‘eater than latter Conciusion The effect of using large dose ofadl‘enaline(5mg J on the cardio—puimonary andcerebraj resuscitation is better,the rate of the re—coverv succese and survival rate Call be raised.
出处
《新乡医学院学报》
CAS
1993年第3期209-212,共4页
Journal of Xinxiang Medical University
关键词
心脏停搏
心肺脑复苏
肾上腺素
cardiac arrest
cardiopulmory resuscitation
cerbral resuscitation
adrenaline
