摘要
应用国产全反式维甲酸(RA)治疗急性早幼粒细胞白血病(APL)14例。结果单用RA治疗,6例完全缓解(CR)率为83.3％,RA合并化疗8例CR率为87.5％,两组总的CR率为85.7％。在治疗中白细胞数明显升高,出血倾向减轻。
Fourteen cases with APL were treated with all-trans retinoic acid(RA). The result showed that in 6 cases with RA alone, CR was 83. 3%,and 8 cases, treated with RA combinated with chemotherapy, CR 87. 5%. A total CR was 85. 7% in two groups. No significant side effects wore found during treatment.
关键词
维甲酸
诱导分化
白血病
all-trans retinoic acid
induced differentiation
acute promyelocytic leukemia (APL)
