肾上腺髓质素与骨代谢研究进展
摘要
肾上腺髓质素 (ADM)是一种多功能调节肽 ,分布于全身骨组织中 ,在体内、体外都对成骨细胞、软骨细胞具有促有丝分裂作用 ,在体内还具有抑制骨吸收作用 ,目前尚未发现对破骨细胞有直接影响。ADM受体与ADM协同表达于成骨细胞、软骨细胞中 ,体现为ADM以自分泌和旁分泌方式调节骨代谢。ADM肽段的成骨活性为骨质疏松症的治疗和骨组织工程种子细胞的制备展示了乐观的前景。
出处
《国外医学（生理病理科学与临床分册）》
2004年第6期516-519,共4页
Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
参考文献22
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