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拓扑异构酶与肿瘤多药耐药及耐药逆转 被引量:5

Topoisomerase in multi-drug resistance and reversal of multi-drug resistance of tunor
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摘要 多药耐药(MDR)的产生是肿瘤化疗失败的主要原因。拓扑异构酶Ⅱ(topoⅡ)介导的 MDR为MDR的重要途径。耐药逆转剂的应用是克服肿瘤临床耐药,提高化疗效果的一种潜在的重 要手段。现综述topoⅡ与肿瘤MDR及耐药逆转研究进展。
出处 《国外医学(肿瘤学分册)》 2005年第2期110-113,共4页 Foreign Medical Sciences (Cancer Section)
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