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干细胞移植治疗急性心肌梗死的研究进展 被引量：2

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摘要 急性心肌梗死(AMI)是心肌的急性坏死,病情凶险,病死率高.目前认为,心肌细胞坏死后心肌细胞不能再生,只能由成纤维细胞填充,最终为瘢痕组织替代,并逐步发生心室重构.而心室重构正是心梗患者发生顽固性心力衰竭和死亡的主要原因[1].
作者 张明 李占全
机构地区 辽宁省人民医院暨辽宁省心血管病医院
出处 《心血管康复医学杂志》 CAS 2005年第1期3-6,共4页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 治疗 干细胞移植 急性心肌梗死(AMI) 心室重构 瘢痕组织 急性坏死 心梗 心肌细胞坏死 研究进展 病情
分类号 R542.22 [医药卫生—心血管疾病] R541 [医药卫生—心血管疾病]
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参考文献30

  • 1Pfeffer MA,Braunwald E.Ventricular remodeling after myocardial infarction:experimental observations and clinical implications[J].Circulation,1990,81:1161-1172.
  • 2Beltrami AP,Urbane K,Kajstura J,et al.Evidence that human cardiac myocyte divide after myocardial infarction[J].New Engl J Med,2001,344:1750-1757.
  • 3Lumelsky N,Blondel O,Laeng P,et al.Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets[J].Sience,2001,292(5520):1389-1394.
  • 4张晓军,屈学民,王斯刚,范云.应用胚胎干细胞研究心肌细胞发育过程的一种模型[J].心脏杂志,2001,13(5):403-405. 被引量：6
  • 5Etizion S,Battler A,Barbash IM,et al.Influence of embryonic cardiomyocyte transplantation on the progression of heart failure in a rat model of extensive myocardial infarction[J].J Mol Cell Cardiol,2001,33(7):1321-1330.
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二级参考文献19

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共引文献108

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二级引证文献6

心血管康复医学杂志
2005年 第1期

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