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超声引导经皮微波凝固治疗肝肿瘤的体会

Percutaneous microwave coagulation therapy for liver cancer under ultrasound
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摘要 目的探讨超声引导下经皮微波凝固治疗肝癌的方法和疗效。方法回顾154例经皮微波凝固治疗的肝癌患者的病史,分析235个肿瘤结节治疗前后声像图表现,CT和AFP改变,评估治疗后患者的复发率、存活率以及治疗产生的副作用和并发症。结果彩超显示94.8%(127/134)肿瘤结节内血流消失;增强CT显示93%(/120/129)肿瘤结节治疗后无增强;83例AFP增高患者中,73.5%(61/83)患者AFP恢复正常,26.5%(22/83)患者呈不同程度下降。肝内复发46例,远处转移11例。累计1,2,3年存活率分别为86%、73%、61%。无严重并发症和副作用。结论微波凝固治疗肝肿瘤安全、疗效确切,对大多数<5cm的肿瘤可达到一次完全灭活的目的,对≥6cm的肿瘤和特殊部位的肿瘤,结合其他方法综合治疗有助提高疗效。 Objective To explore the method and the effect of percutaneous microwave coagulation therapy for liver cacer under ultrasound. Methods To review and analyse 154 cases with liver cancer treated by percutaneous microwave coagulation under US. Results CDFI showed that the intratumoral blood flow was disappeared in 94.8%(127/134)nodules. 93%(/120/129)nodules showed no enhancement on contrast-enhancement CT. AFP level in 73.5%(61/83)cases was normalized and in 26.5%(22/83) cases decreases. Recurrence in liver was 46 cases and remote recurrence was 11cases. The survival rate in 1 to 3 years were 86%?73%?61%. There were no severe complications and side effects. Conclusion Percutaneous microwave coagulation therapy for liver cancer is safe and effective. It is possible to reach the aim of completely eliminating the cancer foci of <5cm in diameter at one stroke. When the cancer foci size is ≥6cm in diameter or location is not suit, it will be effective to combine with other interventional methods.
出处 《上海医学影像》 2004年第4期265-267,286,共4页 Shanghai Medical Imaging
关键词 肝肿瘤 经皮微波凝固治疗 患者 超声引导 AFP 结节 治疗后 并发症 疗效 副作用 Microwave coagulation therapy Liver cancer Ultrasound
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