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狂犬病病毒分子生物学研究进展 被引量：16

Research advance on molecular biology of rabies virus
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摘要 狂犬病是由狂犬病病毒引起的一种重要的人兽共患传染病,一旦发病,100%死亡,目前尚无有效的治疗方法。本文主要综述了狂犬病病毒基因组结构特点及其形态、结构与功能,并详细阐述了狂犬病病毒与毒力、感染及免疫有关的分子生物学基础。 Rabies is an important zoonosis and infectious disease, which was caused by rabies virus. Mortality is the highest in all infectious disease. Until now there are no any therapy methods. Genomic feature, conformation, structure and its functions of rabies virus were discussed in this review. Especially, the molecular basis of rabies virus was expounded, which is related with its virulence, infection and immunization.
作者 袁慧君 王三虎 秦鄂德
机构地区 河南科技学院动物科学系 军事医学科学院微生物流行病研究所
出处 《生物技术通讯》 CAS 2004年第6期596-599,共4页 Letters in Biotechnology
基金 河南省杰出青年基金(04120001600) 河南省自然科学基金(04110033800)
关键词 狂犬病病毒 分子生物学基础 发病 感染 分子生物学研究 人兽共患传染病 死亡 毒力 基因组结构 免疫 rabies virus genomic structure infection immunization
分类号 Q943 [生物学—植物学] R512 [医药卫生—内科学]
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  • 1Otvos L Jr, Krivulka GR, Urge L, et al. Comparison of the effects of amino acid substitutions and beta-N-vs.alpha-O-glycosylation on the T-cell stimulatory activity and conformation of an epitope on the rabies virus glycoprotein[J]. Biochim Biophys Acta,
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生物技术通讯
2004年 第6期

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