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双腔和单腔起搏对高度房室传导阻滞患者血脑钠素水平的影响 被引量：4

Changes of plasma brain natriuretic peptide in patients with high grade atrioventricular(AV) block after dual and single chamber pacing
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摘要 目的　探讨双腔和单腔起搏对高度房室传导阻滞患者血脑钠素水平的影响。方法　 2 0例高度房室传导阻滞患者随机接受人工心脏房室双腔 (n =13 )或心室单腔 (n =7)起搏器 ,起搏器植入术前和术后 10个月分别取静脉血 ,通过放射免疫法测量血浆脑钠素 (BNP)水平。结果　术后 10个月时 ,两组患者血BNP水平均显著高于其术前 ,并且接受单腔起搏的患者血BNP水平明显高于双腔起搏的患者 [(3 5 .85± 5 .2 1)pg/ml比 (2 1.15± 4.16) pg/ml,P <0 .0 5 ]。结论　本实验结果进一步支持双腔起搏可较心室单腔起搏获得更好的血流动力学。
作者 张小勇 谭强 光雪峰 李易 张戈
机构地区 昆明医学院附属第二医院心内科 秦皇岛市第一人民医院心内科
出处 《中国心血管杂志》 2005年第1期54-56,共3页 Chinese Journal of Cardiovascular Medicine
关键词 脑钠素 心脏起搏 房室传导阻滞
分类号 R541.7 [医药卫生—心血管疾病]
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参考文献13

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同被引文献32

  • 1郭诗东,华伟,张澍,王方正,陈柯萍,吴国玫,陈新.右心室间隔部起搏的血流动力学研究[J].中国介入心脏病学杂志,2005,13(2):81-83. 被引量：37
  • 2陈泗林,林纯莹,刘烈,吴书林.主动固定电极在右室流出道间隔部起搏中的应用研究[J].中国心脏起搏与心电生理杂志,2007,21(3):206-208. 被引量：33
  • 3Karpawich PP, Mital S. Comparative left ventricular function following atrial, septal and apical single chamber heart pacing in the young. Pacing Clin Electrophysiol, 1997,20 : 1983.
  • 4Chon JC, Pachon EI Alboronoz RN. Ventricular endocardial right bifocal stimulation in the treatment of severe dilated eardiomyopathy heart failure with wide QRS. PACE, 2001, 24 (9Pt1) : 1369.
  • 5Giudici MC, Thornberg GA, Buck DL, et al. permanent right ventricular outflow t ract pacing improves cardiac output-comparision with apical lead placement in 58 patients. PACE, 1994, 17:776-779.
  • 6Chwab B, Kindermann M, Frohlig G, et al. Septal lead implantation for the reduction of paced QRS duration using passive fixation leads. PACE, 2001,24:28-33.
  • 7Thambo JB,Bordachar P,Garrigue S,et al.Detrimental ventricular remodeling in patients with congenital complete heart block and chronic right ventricular apical pacing[J].Circulation,2004,110(25):3766-3772.
  • 8Schwaab B,Kindermann M,Frohlig G,et al.Septal lead implanta-tion for the reduction of paced QRS duration using passive fixation leads[J].PACE,2001,24(1):28-33.
  • 9Wilkoff BL,Cook JR,Epstein AE.Dual-chamber pacing or ventricu-lar backup pacing in patients with an implantable defibrillator:the dual chamber and VVI implantable defibrillator(DAVID)trial[J].JAMA,2002,285(24):3115-3123.
  • 10Steinberg JS,Fischer A,Wang P,et al.The clinical implications of cumulative right ventricular pacing in the multicenter antomatic de-fibrillator trial Ⅱ[J].J Cardiovasc Electrophysiol,2005,16(4):359-365.

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中国心血管杂志
2005年 第1期

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