摘要
将307例贾第虫感染者分成4个组:即丙硫咪唑10mg/kg/d·3组98例,丙硫咪唑20mg/kg/d·3组105例,甲硝唑20rag/kg/d·3组59例和暂缓治疗组45例。前三组治后1周的近期包囊阴转率分别为91.8％、93.3％和94.9％,三组间比较差异不显著(P均>0.05);治后4周的远期包囊阴转率分别为85.7％、94.3％和96.6％,除B与C组差异不显著外(p>0.05),其余组间差异均显著(P均<0.05)。暂缓治疗组间隔1和4周复查包囊自然阴转率分别仅为4.4％和11.1％。分别与前三组比较差异均极显著(P均<0.01)。结果说明,丙硫咪唑治疗人体贾第虫感染有良好效果,尤以20mg/kg/d·3的疗效为佳。副作用轻微短暂。
A total of 307 children of 3-16 years old with giardiasis were treated with albendazole 10, 20 mg/kg/d. 3 or metronidazole 20 mg/kg/d. 3 or set as blank control. The results showed the negative rate of albendazole or metronidazole in 20 mg/kg/d·3 groups all reached over 93% 1 or 4 weeks after treatment. The side effect in albendazole group was mild and tran- sient.
出处
《实用寄生虫病杂志》
1993年第3期22-24,共3页
Journal of Practical Parasitic Diseases
