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经导管应用双盘状封堵器治疗膜部室间隔缺损56例临床研究 被引量:6

Transcatheter closure of ventricular septal defects using the domestic-made VSD occluder(a report of 56 cases)
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摘要 目的 :探讨经导管应用双盘状封堵器治疗膜部室间隔缺损 ( VSD)及其疗效。方法 :对 5 6例 VSD直径为 3.0~ 1 0 .0 mm2~ 1 5岁患儿 ,经导管置入双盘状封堵器 ,封堵后即刻行左心室造影 ,术后 1 d、3d、7d及 1月行超声心动图检查观察有无残余分流及封堵器位置。结果 :全组 5 6例封堵器植入成功 ,技术成功率 1 0 0 %。术后即刻左心室造影存在微量至少量残余分流 6例 ( 1 0 .7% ) ,5 0例 ( 89.2 % )封堵完全无残余分流。术后 2 4~ 48h超声心动图示分流完全消失 5 4例 ( 96.4% )、微少量残余分流 2例 ( 3.6% )。 1例封堵术后 2 4 h发生溶血 ,经过7d内科保守治疗治愈。2例封堵术后 3d发生 °房室传导阻滞 ,经过 4~ 1 0 d内科保守治疗痊愈。 1月超声心动图未见残余分流及再通。结论 :应用双盘状封堵器治疗室间隔缺损是一种安全有效的介入方法。 Objective:To evaluate the treatment efficiency of transcatheter closure of ventricular septal defect(VSD) using the domestic made occluder device. Methods:56 patients with VSD underwent attempted transcatheter closure of a VSD using the domestic made occluder device at a median age of 8.6±4.3years (range 2.0 to 15).The mean VSD diameter at its left ventricular side was 7.4±2.5mm (rang 3.0~10.0).A 7F or 8F long sheath was used for delivery of the device. The left ventricular graphies(LVG) were performed to evaluate the closure results immediately after the procedure. Echocardiographies and ECG were performed 1 day, 1 month after the closure to find whether there was residual shunt and recanalization. Results:The technical success rate of the group was 100%. LVG showed that 50(89.2%) patients had complete closure immediately. Within 24~48h, color doppler revealed complete closure in 54 patients(96.4%) and a trace to small shunt in 2 patients(3.6%).Two cases suffered with temporary Ⅲ°atrial ventricular block and returned to normal 4~10 days after drug treatment. One patient developed hemolysis 24h after the procedure and recovered 7 days after drug treatment. No residual shunt and VSD recanlization were found in 1 month after the procedure. Conclusion:Transcatheter method of VSD occlusion using domestic made VSD occluder is safe and effective.
出处 《陕西医学杂志》 CAS 北大核心 2005年第1期30-32,共3页 Shaanxi Medical Journal
基金 陕西省自然科学基金项目 (No2 0 0 3 C2 5 3 )
关键词 导管 双盘状封堵器 膜部室间隔缺损 左心室造影 超声心动图 Heart septal defects,ventricular/diagnosis Heart septal defects,ventricular/therapy @Ttranscatheter closure of using the domestic-made VSD occulder device Child
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参考文献8

  • 1Mullasari AS, Umesan CV, Krishnan U, et al.Transcatheter closure of post-myocardial infarction ventricular septal defect with Amplatzer septal occluder . Catheter Cardiovasc Interv, 2001; 54 (4) : 484.
  • 2Hijazi ZM, Hakim F, Al-Fadley F, et al.Transeatheter closure of single muscular ventricular septal defects using the amplatzer muscular VSD occluder : Initial results and technical considerations. Catheter Cardiovasc Interv, 2000;49(2): 167.
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