摘要
目的 探讨急性荨麻疹伴心电图异常改变的致病因素及发病机理 ,寻找有效的防治方法。方法 对急性荨麻疹伴有心前区不适、胸闷、心悸等症状患者 ,治疗前进行心电图检查 ,经治疗荨麻疹消退后复查心电图 ,直到恢复正常。然后停用一切抗组胺药及糖皮质激素药 3天进行变应原检测。结果 心律失常 91例 ,ST—T段改变 81例。吸入组以尘螨( 63 4% )、屋尘 ( 5 8 5 % )、夏秋花粉( 5 4 4% )、多价兽毛 ( 4 9 6% )、多价羽毛 ( 4 4 0 % )等阳性率较高。食物组以芝麻( 5 6 9% )、花生 ( 5 2 8% )、虾 ( 5 1 2 % )、淡水鱼 ( 4 8 0 % )、鸡蛋 ( 4 3 9% )等阳性率较高。结论 急性荨麻疹伴心电图异常改变属I型变态反应疾病 ,变应原检测是为变态反应皮肤病查找变应原的重要手段 ,避免接触变应原是防止变态反应皮肤病再发的有效措施。
Objective To define the pathogenic factors and mechanism of acute urticaria accompanied by abnormal electrocardiogram(ECG)and to search for the effective prevention and treatment.Methods ECG was conducted before and aner treatment in the patients with acute urticaria accompanied by precordial discomfort,tightness in the chest,and palpitation.When ECG returned to normal,the patients stopped taking antihistaminics and glucocorticoids for 3 days,and then allergens were detected.Results Ninety-one patients were found with arrhythmia and 81 with ST-T segment changes.In the inhalation group,higher positive rates were found in acarian dust(63.4%),room dust(58.5%),polyvalcnt animal hair(49.6%)and polyvalent feather(44.0%).In the food group higher positive rates were found in sesame(56.9%),peanut(52.8%),shrimp(51.2%),freshwater fish(48.0%),and hen’s eggs(43.9%).Conclusion Acute urticaria accompanied by abnormal ECG is classified as type l allergic disease, Detection of allergens is an important tool to determine the cause of allergic dermatosis.Avoidance of exposure to allergens is the measure of preventing recurrent disease.This method can be used as one of the effective therapiecs for prevention and treatment of type l allergic dermatosis.
出处
《皮肤病与性病》
2004年第4期6-7,共2页
Dermatology and Venereology
