摘要
目的 观察高氧水耐缺氧、抗疲劳的功能 ,初步研究其作用机制。方法 通过对小鼠体质量值、血清尿素氮、肝糖原、乳酸含量、小鼠负重游泳时间、缺氧生存时间、亚硝酸钠中毒存活时间的测定 ,了解小鼠体能变化情况。结果 小鼠运动后血清尿素氮含量降低 (P<0 .0 5 ) ;肝糖原储备量增加 (P<0 .0 5 ) ;常压耐缺氧生存时间、急性脑缺血性缺氧生存时间均延长 (P<0 .0 5 )。游泳时间虽无明显差异 ,但有延长的趋势。结论 高氧水能增加能量储备 ,提高小鼠的应激生存能力 ,具有耐缺氧。
Objective To investigate the effect of high-oxygen water on anoxia endurance and anti-fatigue function in mice and explore the possible mechanism. Methods KM mice were used. Their body weight, serum urea nitrogen, hepatic glycogen, swimming-sustaining time of mice with a load, plasma lactic acid content, survival time under anoxia or sodium nitrite poisoning were measured. Results It was found that high-oxygen water can prolong swimming time and can protract the anoxia survival time of mice under normal pressure and being afflicted with acute cerebral ischemia (P<0.05). It can also decrease the level of serum urea nitrogen after exercise(P<0.05) and increase hepatic glycogen storage(P<0.05). Conclusion The results demonstrate that high-oxygen water can enhance the emergent survival ability of mice, the ability of fatigue recovery and anoxia endurance function. It also can increase the energy storage.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2005年第1期74-76,共3页
Journal of Sichuan University(Medical Sciences)
基金
四川省高新技术企业科研基金 (编号 0 3 5 10 0 1A0 465 )资助
关键词
高氧水
缺氧
抗疲劳
小鼠
High-oxygen water(HOW) Anoxia Anti-fatigue Mouse
