摘要
脑利钠肽 (BNP)是一种主要从心室分泌的多肽类心脏激素 ,临床测定血浆BNP水平有助于心力衰竭患者的诊断及治疗。最近研究表明在急性冠状动脉综合征的患者中 ,血浆BNP水平明显升高 ,且能够预测急性冠状动脉综合征患者的短期、中期及长期死亡率及非致死性心脏事件 ,可以作为急性冠状动脉综合征危险分层的指标。
Brain natriuretic peptide (BNP) is a 32 amino acid peptide that is synthesized and released predominantly from ventricular myocardium.Circulating plasma levels of BNP are elevated in patients with heart failure and provide diagnostic and prognostic information.Plasma BNP concentrations are also increased significantly in patients with acute coronary syndrome,which will predict the risk of mortality and nonfatal cardiac events in patients with acute coronary syndrome in recent studies.The plasma levels of BNP may serve as a new factor of risk stratification in patients with acute coronary syndrome.
出处
《心血管病学进展》
CAS
2005年第1期49-52,共4页
Advances in Cardiovascular Diseases