Effect of Supercritical Fluids on the Biological Activity of Absidia coerulea for the Hydroxylation of Reichsterin's Substance Acetate
Effect of Supercritical Fluids on the Biological Activity of Absidia coerulea for the Hydroxylation of Reichsterin’s Substance Acetate
摘要
The viability and biological activity of Absidia coerulea in compressed or supercritical CO2 and C2H4 were studied. The specific activity of Absidia coerulea in 7.5MPa CO2 and C2H4 at 306K can reach to 23% and 75% respectively, leading to the feasibility of using supercritical C2H4 as an alternative to the organic solvent in the hydroxylation of Reichsterin’s substance acetate.
The viability and biological activity of Absidia coerulea in compressed or supercritical CO2 and C2H4 were studied. The specific activity of Absidia coerulea in 7.5MPa CO2 and C2H4 at 306K can reach to 23% and 75% respectively, leading to the feasibility of using supercritical C2H4 as an alternative to the organic solvent in the hydroxylation of Reichsterin’s substance acetate.
基金
support from the NNSFC(No.20076033,20176041)is greatly acknowledged
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