摘要
目的评价左氧氟沙星(levofloxacin,LVX)与头孢曲松(ceftriaxone,CRO)配伍甲硝唑(metronidazole,Met)预防及治疗急性阑尾炎围手术期感染的疗效。方法采用前瞻性、随机、对照研究方法,将60例急诊阑尾炎手术患者分别采用LVX、CRO配伍Met,围手术期静脉滴注,预防腹腔及切口感染。结果两组患者体温、血生化指标恢复、临床疗效、切口感染率、细菌敏感率差异均无明显性。结论左氧氟沙星与头孢曲松配伍甲硝唑预防及治疗急性阑尾炎围手术期感染,均具有较好的临床疗效。
OBJECTIVE To study the prophylaxis and treatment effects of levofloxacin (LVX)/ceftriaxone (CRO) plus metronidazole(Met)on the infection during the perioperation of appendectomy in acute appendicitis. METHODS Sixty patients of appendicitis were administered with LVX or CRO plus Met intravenously in a randomized prospective study. The prophylaxis and treatment effects were evaluated on the abdominal and wound infection during the perioperation. RESULTS Two groups of patients have no significant difference in body temperature, results of blood routine test, clinical response, wound infection rate, and bacteriological susceptibility rate. CONCLUSIONS Both levofloxacin/ceftriaxone plus metronidazole are well suited to the infection during the perioperation of appendectomy.
出处
《中华医院感染学杂志》
CAS
CSCD
2004年第12期1410-1412,共3页
Chinese Journal of Nosocomiology
