摘要
目的:了解我院小儿败血症的抗菌药使用情况,以提高用药的合理性。方法:回顾性分析61例小儿败血症的致病菌、药敏试验及抗菌药使用等临床资料。结果:61例均为单一菌种致病,包括葡萄球菌属23例,肺炎克雷伯菌18例,大肠埃希菌14例,绿脓杆菌6例。葡萄球菌属对万古霉素高度敏感,其次为苯唑青霉素;肺炎克雷伯、大肠埃希菌、绿脓杆菌对碳青霉烯类敏感,其次对头孢三代抗菌药及阿米卡星敏感。各类抗菌药使用频度由高到低依次为β鄄内酰胺类、氨基糖苷类、万古霉素。全部二联用药,以β鄄内酰胺类+氨基糖苷类、2种β鄄内酰胺类联合为主。结论:我院治疗小儿败血症的抗菌药使用情况基本合理。
Objective: To summarize antibiotic use in treatment of pediatric septic patients in our hospital and to improve rationality of antibiotic use. Methods: Clinical data of 61 pediatric patients with septemia, including pathogenic bacterium, antibiotic sensitivity test and antibiotic use, were analysed retrospectively. Results: 61 cases were all infected with single pathogenic bacterium, including 23 cases with staphylococci, 18 cases with Klebsiella, 14 cases with Escherichia coli and 6 cases with Pseudomonas aeruginosa. Staphylococci were highly sensitive to vancomycin, less sensitive to oxacillin. Klebsiella, Escherichia coli and Pseudomonas aeruginosa were sensitive to carbopene, less sensitive to third generation cephalosporin and amikacin. The using frequency of each antibiotic species from high to low were tics, aminoglycoside and vancomycin in turn. All cases were treated with two antibiotics synergetically, mainly temia was basically rational in our hospital.
出处
《儿科药学杂志》
CAS
2004年第6期29-30,共2页
Journal of Pediatric Pharmacy
关键词
小儿
败血症
抗菌药
用药分析
Pediatric
Septemia
Antibiotic use
Analysis
