摘要
对20例腮腺原发性恶性淋巴瘤,作了临床病理和免疫组化的研究,结果B细胞来源9例(45%),T细胞来源8例(40%),小淋巴细胞性3例(15%),11例作了免疫组化,除1例原病理诊断为淋巴浆细胞性而免疫表型为T细胞外.余10例前后诊断相符,20例随访获得随访结果的16例中,3例在一年内死于肿瘤,其中B裂细胞性、淋巴母细胞性及多形T细胞性各1例;目前仍存活的13例,存活了15个月至9年3个月,其中低度恶性2例(均为小淋巴细胞性),中度恶性7例(B裂细胞性5例,B混合细胞性2例),高度恶性4例(透明细胞性2例,多形T细胞住2例).均经手术加中西医综合治疗,预后良好。
A clinico-pathologic and immunohistochemical study of 20 cases of primary nonHodgkin's lymphoma on the parotid gland was made.The result showed 45% of the cases originated from B cells,white 40% from T cells,the rest 15% from the small lymphocytes.Immunohistochemical study was made on 11 cases,the result of immunophenotype was in concordance with the histopathologic diagnosis in 10 cases,except in one case which was initially diagnosed as plasmocytoid lymphocytic lymphoma,but the immunophenotype suggested that it was Tcell type of malignant lymphoma(ML).Follow-up data can be collceted in 16 cases(80%).Three of the 16 cases(18.75%)died of the tumor within one year,they were diagnosed initially as B cleaved cell,lymphoplastic cell and polymorphic T cell type of ML,each in 1 case.Other cases survived from 15 months to 9.25 years,among them 2 were diagnosed as low-grade ML(both of small lymphocyte type),7 cases as middle-grade ML(5 of B cleaved cell,2 of B mixed type),and 4 cases as high-grade ML(2 of clear T cell,2 of polymorphic T cell type).They were treated by surgical removal and combined western and traditional Chinese medicine,their prognosis was quite good.
出处
《上海口腔医学》
CAS
CSCD
1994年第3期139-141,共3页
Shanghai Journal of Stomatology