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心肺复苏中联合应用肾上腺素与纳洛酮的研究 被引量:2

Study of applying of epinephrine with naloxone hydrochloride to patients during cardiopulmonary resuscitation
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摘要 目的 探讨肾上腺素配合纳洛酮在心跳停止时间超过 5分钟的患者复苏中的效果。方法 选取心跳停止 5分钟以上患者共计 14 3例 ,分为 3组。复苏时给予不同剂量的上腺素及纳洛酮。结果 通过对 3组患者复苏期间 10、2 0、30分钟时血压、心跳结果记录 ,显示方法 3组的患者在心脏复跳人数及血压恢复人数两项指标数均超过方法 1组及方法 2组。在呼吸、瞳孔变化及意识恢复方面无显著性差异。结论 大剂量肾上腺素加用纳洛酮的应用 ,在心肺复苏中 ,能明显提高心脏复跳率 ,在复跳后的血压恢复方面疗效亦较好。但对患者呼吸的恢复及脑复苏 ,暂不能证明有很好的效果。 Objective To investigate the effects of using epinephrine with naloxone hydrochloride on patients whose cardiac arrest time is over 5 minutes during cardiopulmonary resuscitation.Methods The 143 cases with cardiac arrest over 5 minutes were divided into three groups.During the cardiopulmonary resuscitation, the epinephrine and naloxone were given to patients by intravenous injection with different dose in different group.Results Through the result records of blood pressure and heartbeat from patients at the time of 10,20 and 30 minutes during their cardiopulmonary resuscitation,the cases in group 3 are superior to group 1 2 in the number of patients with their heart beating again and blood pressure recovering.However,there are no remarkable differences in breath,pupil change and awareness recovery.Conclusion As the result of applying the high-dose epinephrine with naloxone hydrochloride to the cases during the cardiopulmonary resuscitation, it's obviously better to highten the rate of heart beating again and the blood pressure recovery, but its good effects of breath recovery and brain resuscitation on cases remain to be found.
作者 高超 刘建中
出处 《宁夏医学杂志》 CAS 2004年第11期680-682,共3页 Ningxia Medical Journal
关键词 心肺复苏 肾上腺素剂量 纳洛酮 Cardiopulmonary resuscitation Epinephrine dose Naloxone hydrochloride
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