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口服佐洛复、万艾可或可多华治疗早泄的疗效比较 被引量:12

Efficacy and safety of Sertraline, Viagra and Cardura in patients with premature ejaculation
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摘要 目的比较佐洛复、万艾可和可多华治疗早泄的临床效果。方法120例早泄病人随机分成4组:对照组(单纯行为疗法组)、可多华+行为疗法组、万艾可+行为疗法组和佐洛复+行为疗法组,记录病人治疗前后阴道内射精潜伏期并进行组内和组间比较,同时记录夫妻对性生活的满意程度。结果治疗前4组阴道内射精潜伏期分别为(0.8000±0.1983)min、(0.8933±0.3216)min、(0.7333±0.2397)min和(0.8500±0.2910)min,治疗后分别为(1.8200±0.5413)min、(2.6467±0.6726)min、(3.6333±0.5542)min和(4.8533±0.5710)min。从夫妻对性生活满意度来看,疗效由低到高也分别为单纯行为疗法组、可多华+行为疗法组、万艾可+行为疗法组和佐洛复+行为疗法组。结论在治疗早泄方面,佐洛复优于万艾可和可多华,可作为治疗早泄的一线用药。如病人合并勃起功能障碍,可试用万艾呵,如病人合并前列腺增生可试用可多华,但万艾可和可多华治疗早泄的临床资料不多,尚需进一步研究。 Objective To compare the efficacy of Sertraline, Viagra and Cardura for the treatment of premature ejaculation (PE). Methods 120 PE patients were divided into four groups randomly: control group (only behavior therapy group), Cardura with behavior group, Viagra with behavior group and Sertraline with behavior group. Intra-vaginal ejaculation latency time (IELT) was recorded before and after treatment and also the coitus satisfaction degree of patient and partner. Results Before treatment, the IELT of four groups are (0.8000±0.1983)min, (0.8933±0.3216)min, (0.7333±0.2397)min and (0.8500±0.2910)min respectively; after treatment, the IELT are (1.8200±0.5413 )min, (2.6467±0.6726)min, (3.6333±0.5542)min and (4.8533±0.571) min respectively. In the face of satisfaction degree, Sertraline is better than Viagra, Viagra is better than Cardura and Cardura better than behavior. Conclusion For treating PE, Sertraline is the best during the clinical trial and may be the first choice for the pharmacotherapy of PE. If PE patient simultaneously has erectile dysfunction, Viagra may be used; if PE patient has simultaneously benign prostate hyperplasia, Cardura may be used. However, the clinical material of the efficacy of Viagra and Cardura for PE treatment is little, more research work should be done.
出处 《中国男科学杂志》 CAS CSCD 2004年第6期20-22,25,共4页 Chinese Journal of Andrology
关键词 早泄 佐洛复 万艾可 可多华 行为疗法 premature ejaculation Sertraline Viagra Cardura behavior therapy
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参考文献9

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二级参考文献3

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