摘要
目的 检测肺炎链球菌、流感嗜血杆菌和卡他莫拉菌的耐药性。方法 标本分别接种羊血平板和巧克力平板 ,用标准方法进行菌种鉴定 ;用微量肉汤稀释法分别测定其最低抑菌浓度。结果 青霉素不敏感肺炎链球菌占 2 5 .6 % ,左氧氟沙星、万古霉素和β 内酰胺类抗生素对肺炎链球菌有很高的抗菌活性 ,大环内酯类和复方磺胺甲唑耐药率较高 ;流感嗜血杆菌和卡他莫拉菌的产 β 内酰胺酶率分别为 32 .7%、91.3% ;头孢菌素对这3种细菌都有较高的抗菌活性。结论 头孢菌素是治疗 3种细菌感染的首选药物。
Objective To analyze the resistance of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. Methods Samples were inoculated onto sheep blood agar plates and chocolate agar plates respectively and bacteria were identified with standard method. The minimal inhibitory concentrations were measured by broth microdilution method. Results Non-penicillin-susceptible Streptococcus pneumoniae was 25.6%. Levofloxacin, vancomycin and β-lactam antibiotics showed very high activities to Streptococcus pneumoniae. Resistance to macrolides and trimethoprin/sulfamethoxazole were higher. The rate of producing β-lactamases of Haemophilus influenzae and Moraxella catarrhalis was 32.7% and 91.3% respectively. These three kinds of bacteria were all sensitive to cephalosporins. Conclusions Cephalosporins are the first candidate for the infectious conditions caused by the above three kinds of bacteria.
出处
《检验医学》
CAS
北大核心
2004年第6期556-558,共3页
Laboratory Medicine
关键词
肺炎链球菌
流感嗜血杆菌
卡他莫拉菌
耐药性
Streptococcus pneumoniae
Haemophilus influenzae
Moraxella catarrhalis
Minimal inhibitory concentration
