摘要
目的 评价甲状腺功能亢进症 (简称甲亢 )的 6种实验室检查项目的诊断准确性。方法 采用放射免疫方法和免疫放射方法分别测定 15 0例甲亢患者及 10 0名正常人的总T3(TT3)、总T4 (TT4 )、游离T3(FT3)、游离T4 (FT4 )、反T3(rT3)及超敏促甲状腺素 (s TSH) ,并绘制ROC曲线及计算曲线下面积。结果 各项目的ROC曲线下面积为 :Ss TSH=0 .95 7、SFT3 =0 .95 2、STT3 =0 .933、SFT4=0 .90 5、SrT3 =0 .899、STT4=0 .874。结论 s TSH和FT3的诊断准确性最好 ;ROC曲线是一种科学、全面评价检验指标的检验方法。
Objective To evaluate the accuracy of six laboratory tests for the diagnosis of hyperthyroidism. Methods The levels of TT3,TT4,FT3,FT4,rT3 and s-TSH in 150 patients with hyperthyroidism and 100 normal persons were measured by RIA and IRMA. Receiver operating characteristic (ROC) curve was drawn, and the area under the curve was calculated. Results The area under ROC curve of S s-TSH ,S FT3 ,S TT3 ,S FT4 ,S rT3 and S TT4 was 0.957,0.952,0.933,0.905,0.899 and 0.874 respectively. Conclusions The accuracy of s-TSH and FT3 is the best in diagnosis of hyperthyroidism according to the ROC curve evaluation.
出处
《检验医学》
CAS
北大核心
2004年第6期528-530,共3页
Laboratory Medicine
基金
重庆市巴南区科委科研基金资助项目 ( 2 0 0 2 13 )
