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p53、p16、p27和PTEN基因与卵巢癌的关系

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摘要 卵巢癌是一种严重威胁妇女生命健康的妇科常见恶性肿瘤,极易在早期发生浸润和转移,由于其具有起病隐匿、早期临床诊断率低、复发率高等特点,严重影响远期疗效。5年生存率只有25%~30%,死亡率居妇科恶性肿瘤首位。随着肿瘤研究的不断深人和分子生物学的飞速发展,已经发现了多种癌基因和抑癌基因,人们已经认识到恶性肿瘤除了与癌基因的表达与恶性病变有关以外,抑癌基因的失活也起到非常重要的作用。因此如何利用新方法。
出处 《中国医学文摘(肿瘤学)》 2004年第3期234-235,共2页 Journal of Chinese Medical Abstracts·Oncology
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参考文献11

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二级参考文献6

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