摘要
为探讨系统性红斑狼疮 ( SLE)患者血清中抗 ENA抗体与抗 DNA抗体的关系及意义 ,对 88例 SL E患者分别测定血清中抗 ss-DNA抗体、抗 ds-DNA抗体及 7种抗 ENA抗体。结果显示 ,88例 SLE患者中有 65例 ( 73 .5 % )检测到至少一种抗 ENA抗体 ,以抗 Sm、抗 U1 RNP和抗 SSA为主 ,分别占 45 .5 %、5 2 .3 %及 40 .9% ,其次为抗 SSB及抗 Rib,分别占 2 5 .0 %及 15 .9%。 88例SLE患者的 7种自身抗体与抗 ds-DNA抗体总的阳性符合率为 75 .2 % ,与抗 ss-DNA抗体总的阳性符合率为 60 .2 %。因此 ,抗 ENA抗体与抗 DNA抗体同时检测有助于提高 SLE的诊断阳性率。
To investigate the relation and meaning of anti-ENA and anti-DNA in patients with SLE,determination in diagnosis of anti-ss-DNA、anti-ds -DNA and seven anti-ENA in 88 patients with SLE. It was found that 65 cases(73.9%) were detected at least one anti-ENA,the mainly anti-ENA were anti-Sm (45.5%)、 anti-U 1RNP(52.3%) and anti-SSA(40.9%),the next were anti-SSB(25.0%) and anti-Rib (15.9%).The positive coincidence proportion between seven anti-ENA and anti-ds-DNA were 75.2%,and 60.2%with anti-ss-DNA in 88 patients with SLE.It was help to improve the SLE diagnosis positive proportion while anti-ENA and anti-DNA were detected at the same time.
出处
《数理医药学杂志》
2004年第5期418-419,共2页
Journal of Mathematical Medicine
