摘要
目的:建立准确、稳定的含量测定方法,有效地控制制剂质量。方法:以酸水解-有机溶媒提取,HPLC法测定样品中游离大黄素及总大黄素的含量。结果:样品中大黄素得到较好的分离,上述两种成分加样回收率分别为101.30％,98.46％;RSD分别为1.51％,1.75％。结论:本法能有效地控制该制剂的质量。
Objective: Setting an accurate quantitative determination metnod to control the preparation quality. Method Emodin in preparation was extracted by acid hydrolysis and organic solvent, then was determined by HPLC. Result The recovery of free Emodin was 101.30％, RSD was 1.51％, and of total Emodin was 98.46％, RSD 1.95％. Conclusion: The quantitative determination method can be used for the quality control of Huangjie Capsules.
出处
《中国药品标准》
CAS
2000年第1期44-45,共2页
Drug Standards of China
