摘要
脊髓损伤修复过程中不仅缺乏生长促进物质,而且存在大量抑制性基质。胶质瘢痕是脊髓损伤后所面临的主要抑制环境,参与胶质瘢痕主要的细胞成分有星形胶质细胞、小胶质细胞、少突胶质细胞的前体细胞,有时还包括脊膜细胞和干细胞,而每一种细胞又分泌许多抑制性基质。有效地防止瘢痕形成,减少抑制性基质的分泌,就能为神经再生提供更有利的微环境。目前的方法有去除产生抑制性分子的细胞,防止合成抑制性分子,封闭抑制性分子和降解抑制性分子或增加营养因子。
出处
《国外医学（神经病学．神经外科学分册）》
2004年第4期380-383,共4页
Foreign Medical Sciences（Section On Neurology & Neurosurgery）
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