摘要
目的 :总结经纤维支气管镜局部用药治疗晚期肺癌患者的疗效。方法 :将 72例晚期肺癌患者 ,随机分为治疗组 ( 38例 )和对照组 ( 34例 )。治疗组采用日本 OlympusBF2 0及配套的 NM- 3K型注射针在肿瘤局部注入化疗药物并全身静脉化疗 ,对照组单纯用全身静脉化疗。结果 :治疗组 38例中 ,完全缓解 1 5例 ,占 39% ,部分缓解 1 9例 ,占 5 0 % ,无变化 4例 ,占 1 1 % ,有效率 89% ,明显高于对照组 ( P<0 .0 5 )。结论 :经纤支镜局部化疗同时联合全身静脉化疗可明显缓解因肺癌原发灶、转移灶所引起的阻塞症状。此联合方法的客观疗效和症状缓解均优于单纯全身化疗。
Objective:To investigate the effectiveness of treatment in advanced lung carcinoma with bronchoscopic chemotherapy combined with systemic chemotherapy. Methods: Forty-three patients with advanced lung carcinoma confirmed by pathology were divided into treated group(n=38)and control group(n=34)randomly. The treated group recieved intravenous chemotherapy with the routine regimen and bronchoscopic injection into the tumor and the surroundings,while the control group were treated only by intravenous chemotherapy with the same routine regimen. Results: 15 patients in the treated group (39%)were cured completely,19 patients in this group(50%)had partial recovery,and 4 patients (11%) showed no effec. The effective rate was 89%.In the control group(n=34),6 patients(17.4%)were cured completely and 13(39.2%)achieved partial recovery,while 15(43.4%) patients had no effect.The effective rate was 55.9%.The efficacy of treated group was significantly higher than the control group(P<0.05). Conclusion: Advanced lung cracinoma treated by Bronchoscopic local chemotherapy and with intravenous systemematic chemotherapy showed reduced size of tumor, relieved clinical symptoms and increased survival rate.For patients with advanced lung cancer,this is an effective palliative treatment.
出处
《陕西医学杂志》
CAS
北大核心
2004年第10期900-902,共3页
Shaanxi Medical Journal
