摘要
通过对家蚕 (Bombyxmori)大规模EST的分析 ,发现家蚕的chi、gluE和 fruA基因分别与微生物的相应基因存在高度的氨基酸序列同源性 ,且进化关系很近 ,但与线虫 (Caenorhabditiselegans)、果蝇 (Drosophilamelanogaster)、按蚊 (Anophelesgambiae)以及家蚕近缘昆虫的类似基因之间的相似性却非常低。这表明它们可能分别与微生物的同源基因具有共同的祖先 ,即微生物的基因水平转移给了家蚕 。
According to the analysis of large scale EST sequencing of silkworm,Bombyx mori,we found that chi,glue and fruA of silkworm have very high homology at amino acid level and closely phylogenetic relative with that of microorganism,but lower similarity with genes of eelworm (Caenorhabditis elegans),fruitfly (Drosophila melanogaster),mosquito (Anopheles gambiae) and other relative insects,respectively.It indicates that each of them is likely to have common ancestor with that of microorganism.Namely,microbial genes were likely transferred to silkworm by horizontal gene transfer,instead of the vertical inheritance in evolutionary manner.
基金
国家自然科学基金项目 (编号 :3 0 2 70 691)
教育部留学回国人员科研启动基金资助项目 (编号 :2 0 0 3 40 6)~~
关键词
基因水平转移
几丁质酶基因
系统进化
家蚕
horizontal gene transfer
chitinase gene
phylogenesis
Bombyx mori
