摘要
目的 为了调查单纯疱疹病毒Ⅱ型在男性和女性患者中的感染情况。方法 用荧光定量PCR技术对 5 9例男性和 4 0例女性生殖器溃疡和疱疹患者进行HSVⅡDNA检测。结果 男性平均年龄 35 .0 7± 10 .77,女性 2 9.35± 5 .91,t=2 .5 5 ,p =0 .0 14 ;男性HSVⅡDNA阳性率为 2 7.12 % ,定量拷贝对数为 7.72 5± 1.4 74 ,女性HSVⅡDNA阳性率为 17.5 % ,定量拷贝对数为 6 .92 7± 1.84 2 ( χ2 =1.2 37,P =0 .2 6 6 ;t=1.10 1,P =0 .2 80 )。结论 男性年龄高于女性年龄 ,男性和女性间感染阳性率无差异 ,急性感染的发生率也基本一致。
Objective: To investigate the infection of herpes simplex virus Ⅱin genital in male and female patients.Methods: Fluorescence quantitative PCR (FQ-PCR) was used to detect quantitatively herpes simplex virus Ⅱ DNA in 59 cases of male and 40 cases of female of genital ulcer disease(GUD) and simplex.Results: The mean age of male was 35.07±10.77 and the female was 29.35±5.91,t=2.55,P=0.014;The positive rate of HSV-Ⅱ DNA in male was 27.12%. The logarithm of HSV-Ⅱ DNA copies was 7.725±1.474;The positive rate of HSV-Ⅱ DNA in female was 17.5%.The logarithm of HSV-Ⅱ DNA copies was 6.927±1.842. (χ 2=1.237,P=0.266;t=1.101,P=0.280). Conclusion: The age of male was higher than the female. The positive rate of male and female had no significant difference in statistics.The rate of acute infection was same.
出处
《中国优生与遗传杂志》
2004年第5期32-32,31,共2页
Chinese Journal of Birth Health & Heredity
