摘要
阿尔茨海默病是老年痴呆中最常见的原因。FDGPET可以探测AD与不同类型痴呆葡萄糖代谢的早期变化,用于AD的早期诊断与鉴别诊断。神经炎性斑块和神经纤维缠结是AD主要的病理学特征。淀粉样斑块PET显像可以提供AD早期的诊断信息。本文主要介绍FDG与淀粉样斑块PET显像在AD中的应用价值。
Alzheimer disease(AD)is the most common cause of dementia in the current elderly populaˉtion.FDG PET can detect early metabolic changes in AD and differential metabolic features of various dementia,and be used in the early diagnosis and differential diagnosis of AD.Neuritic plaques(NPs)and neurofibrillary tangles(NFTs)are the two most characteristic pathologic hallmarks of AD.Amyloid imaging with positron emission tomography could provide important information on early or presympˉtomatic cases of dementia.This paper will focus to evaluate the value of FDG and amyloid PET imaging in Alzheimer's disease.
出处
《中国医学计算机成像杂志》
CSCD
2004年第5期352-358,共7页
Chinese Computed Medical Imaging