摘要
目的 通过观察梁氏抗风湿类风湿冲剂对类风湿性关节炎活动期患者的影响,评价其有效性。方法依据诊断标准选取类风湿性关节炎活动期患者80例,按随机数字表法分为治疗组(50例)和对照组(30例)。治疗组服梁氏抗风湿类风湿冲剂,对照组服 痹冲剂,60d为1个疗程。60d后对比观察患者治疗前后临床疗效、症状体征、实验室理化指标及血液流变学各项指标的变化情况。结果 治疗组愈显率为80.0%,总有效率为 94.0%,均明显优于对照组(P < 0.01);在改善关节疼痛、肿胀、功能障碍指数和晨僵、15米步行时间的积分方面,血沉(ESR)、类风湿因子(RF)、C反应蛋白(CRP)、免疫球蛋白 G(IgG)、免疫球蛋白 A(IgA)等实验室理化指标以及全血粘度、血浆粘度、全血还原粘度、红细胞压积、纤维蛋白原等血液流变学各项指标方面,较治疗前有显著性差异(P < 0.05或 P < 0.01),也优于对照组(P < 0.05或 P < 0.01)。结论 梁氏抗风湿类风湿冲剂是治疗类风湿性关节炎活动期较为有效和理想的药物。
Objective To evaluate the effectiveness of Liang’s Kang-fengshi-leifengshi Chongji to the active phase of rheumatoid arthritis (RA). Methods Eighty patients with the active phase of RA were selected according to the diagnostic standard, and randomly divided into therapy group ( n = 50) and control group (n = 30). Patients in the therapy group were treated with Liangg’ Kang-fengshi-leifengshi Chongji, and patients in the control s group were treated with Wangbi Chongji, sixty days as a course. After 60 days, the clinical effect, symptom and physical sign, the change of biochemical criterion of ESR, RF, CRP and IgG、IgA、IgM, and the change of hemorheologic markers of patient before and after therapy were observed. Results In the therapy group, the healing and marked effective rate was 80.0%, and the total effective rate was 94.0%. Both were obviously better than those of the control group (P < 0.01). In ameliorating capital symptom, physical sign, biochemical criterion of ESR, RF, CRP and IgG, IgA, and hemorheologic markers of patient, those after therapy were significantly different from those before therapy in the therapy group (P < 0.05 or P < 0.01) , and they were better than those of the contaol gqoup (P < 0.05 or P < 0.01). Conclusion Liang ’s Kang-fengshi-leifengshi Chongji is an effective and ideal TCM agent for the active phase of RA. 〔
出处
《深圳中西医结合杂志》
2004年第5期257-260,共4页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
类风湿关节炎
活动期
梁氏抗风湿类风湿冲剂
临床观察
Rheumatoid arthritis (RA)
Active phase
Liang’s Kang-fengshi-leifengshi Chongji
Clinical observation
