摘要
目的评价大剂量甲基强的松龙对原田病急性期浆液性视网膜脱离的治疗作用。方法对2001-12/2003-07就诊本院患者11例(22眼)在临床诊断当天即给予甲基强的松龙静脉滴注,剂量为500mg,1次/d,连续用3d后迅速减量,于7d内减为强的松口服。OCT和间接眼底镜观察炎症渗出吸收情况,检查视功能恢复情况。结果大剂量甲基强的松龙静脉滴注次日即可观察到22眼视网膜下液均明显减少,静滴3d后浆液性视网膜脱离基本消失,视网膜复位,出院时21眼视网膜下液完全吸收,14眼(64%)视力恢复至0.5以上。结论甲基强的松龙冲击疗法可促进原田病急性期视网膜下液迅速吸收,恢复视功能,疗效可靠,值得临床推广。
AIM: To evaluate the rapid effect of pulse methylprednisolone therapy on serous retinal detachment at the acute phase of Harada disease.· METHODS: Eleven cases (22 eyes) at the acute phase of initial Harada disease with serous retinal detachment were treated with pulse methylprednisolone therapy in our hospital from December, 2001 to July, 2003. Optical coherence tomography (OCT) and binophthalmoscopy were used to follow the resolution of the retinal detachment and macular edema.· RESULTS: After 3 consecutive days of intravenous drip-infusion of methylprednisolone 500mg/d, the retinal detachment was almost completely controlled and the macular edema was absorbed progressively. The dose of methylprednisolone was diminished at 3d and replaced by oral prednisolone in 7d. Fourteen eyes (64%) achieved visual acuities of 0.5 or better.· CONCLUSION: Pulse methylprednisolone therapy can improve the absorption of serous fluid at the acute phase of Harada disease with good effects, thus should be generalized in clinic.·
出处
《国际眼科杂志》
CAS
2004年第5期865-867,共3页
International Eye Science
