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108例2型糖尿病3种短期胰岛素强化治疗方法的临床研究 被引量:1

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摘要 目的 :观察 3种不同短期胰岛素强化治疗方法对 2列糖尿病的降糖作用和评价常规人胰岛素和胰岛素Aspart应用于胰岛素泵的特点。方法 :对 1 0 8例空腹血糖大于 1 1 1mmol/L的 2型糖尿病患者随机分为常规人胰岛素强化治疗组 (MSII组 )、胰岛素泵持续人胰岛素输注强化治疗组 (CSII-R组 )和胰岛素泵持续胰岛素Aspart输注强化治疗组 (CSII-A组 ) ,比较血糖治疗达标所需天数、日均胰岛素用量、低血糖频率、泵应用的餐前大剂量和基础量及血糖控制水平。结果 :CSII-R组和CSII -A组血糖达标天数分别为 4 7± 1 6,4 8± 1 2 )比MSII组缩短1 3 8天 (P <0 0 0 0 1 ) ,胰岛素用量比MSII组显著减少 (均P <0 0 5 ) ,CSII-R组和CSII-A组未发生低血糖 ,MSII组低血糖发生 1 9人次。血糖治疗达标后至停止泵治疗时 ,CSII-A组胰岛素基础剂量比CSII -R组显著增多 (均数增加 1 4 2 % ,P <0 0 5 ) ,餐前大剂量显著减少 (均数减小 1 7 4% ,P <0 0 5 ) ;CSII-A组餐后血糖较CSII-R组显著降低 (均数降低 1 3mmol/L ,P <0 0 1 ) ,前者发生低血糖 1人次 ,后者 6人次。结论 :胰岛素泵CSII强化治疗 2型糖尿病具有快速、稳定、理想地控制血糖的作用 。
出处 《辽宁实用糖尿病杂志》 2004年第5期25-27,共3页 Liaoning Journal of Practical Diabetology
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参考文献9

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二级参考文献27

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