摘要
目的 探讨急性心肌梗死 (AMI)溶栓治疗前后P波终末电势 (PTFv1)、P波离散度 (Pdisp)的变化。方法 选择86例溶栓的AMI患者 ,根据溶栓后冠脉是否再通分为 :再通组62例 ,未通组24例。测量所有患者溶栓前、溶栓后3h和1周之体表12导联心电图的PTFv1、Pdisp。 结果 再通组和未通组溶栓前的PTFv1分别为 -0.0352±0.0135和 -0.0347±0.0147mm.s,Pdisp分别为44.57±10.4和43.95±10.63ms,两组分别比较均无显著差异 ( p均>0.05) ,但两组溶栓后3h和1周的PTFv1、Pdisp分别比较 ,均有显著差异 ( p均<0.05)。再通组在溶栓后3h和1周PTFv1为 -0.0308±0.014和 -0.0303±0.0141mm.s,Pdisp为37.66±10.43和36.94±12.38ms ,分别与溶栓前的PTFv1、Pdisp比较 ,均有显著差异 ( p均<0.001) ,但溶栓后3h与溶栓后1周的PTFv1、Pdisp分别比较 ,无显著意义 ( p>0.05)。未通组的PTFv1、Pdisp在溶栓前后比较 ,均无显著意义 ( p均>0.05)。62例冠脉再通患者 ,溶栓前12例发生房性心律失常 ,其Pdisp为51.94±7.07ms,而50例无房性心律失常 ,其Pdisp为42.79±10.33ms,两者比较有显著差异 ( p<0.01) ,溶栓后1周两者Pdisp相比差异无显著意义(p>0.05) ;而PTFv1在溶栓前或溶栓后 ,两者分别比较 ,均无显著意义 (p>0.05)。结论 AMI溶栓后冠脉再通?
Objective To investigate the effect of thrombolysis on V1p-wave terminal force(PTFv1),p-wave dispersion(P disp)in the patients with acute myocardial infarction(AMI). Methods 86patients with AMI,who had received intravenous thrombolytic therapy,were divided into two groups according to reperfusion and non-reperfusion of the coronary arteries,reperfusion group consisting of62patients and non-reperfusion group24patients.12-lead electrocardiogram(EKG)were measured in all patients before and3hours 1week after thrombolysis. Results PTFv1and Pdisp in the patients before thrombolysis had no significant difference between reperfusion and non-reperfusion group(P>0.05),but there was significant difˉference between two groups in the patients3hours 1week after thrombolysis.In the reperfusion group,PTFv1and Pdisp were-0.0352±0.0135mm.s and44.57±10.40ms in the patients before thrombolysis,and-0.0308±0.0140mm.s and37.66±10.43ms in the patients3hours after thrombolysis,and-0.0303±0.0141mm.s and36.94±12.38ms in the patients1week after thrombolysis.There was significant difference between before and after thrombolysis(P<0.001).However,in the non-reperfusion group,PTFv1and Pdisp had no significant difference between before and after thrombolysis(P>0.05).Atrial arrhythmia in the reperfusion group occurred in12patients whose Pdisp was51.94±7.07ms before thrombolysis,otherwise,in other50patients whose Pdisp was42.79±10.33ms before thrombolysis,there were no atrial arrhythmia.There was significant difference(P<0.01)before thrombolysis and no significant difference(P>05)1week after thrombolysis.PTFv1in the reperfusion group had no significant difference between the patients who had and no atrial arrhythmia before or1week after thrombolysis. Conclusion PTFv1and Pdisp can be improved and the incidence of atrial arrhythmia can be decreased by successful intravenous thrombolytic treatment in AMI patients.
出处
《浙江临床医学》
2004年第10期835-836,共2页
Zhejiang Clinical Medical Journal
关键词
溶栓治疗
P波终末电势
冠脉再通
P波离散度
患者
房性心律失常
急性心肌梗死
V1p-wave terminal force(PTFv1),p-wave dispersion(Pdisp),Acute myocardial infarction(AMI),Intravenous thrombolytic treatment.
