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老年慢性充血性心力衰竭患者血清甲状腺激素变化的临床分析 被引量:1

Changes of thyroid hormone of senile patients with chronic congestive heart failure
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摘要 目的观察老年慢性充血性心力衰竭 (CHF)患者血清甲状腺激素的变化 ,探讨与心衰程度和预后的关系。方法采用化学发光法测定观察组和对照组血清游离三碘甲状腺原氨酸 (FT3 )、游离甲状腺素 (FT4)、促甲状腺素 (TSH)各参数水平 ,并与对照组比较。结果与对照组比较 ,FT3 明显降低 ,差异有显著意义 (P <0 0 5 ) ;FT4降低仅见于部分心功能Ⅳ级患者 ;TSH无明显改变。结论老年人CHF患者存在甲状腺激素代谢异常 ;FT3 降低与心衰程度呈正相关 ,并可作为CHF患者病情和预后判断的指标。 Objective To observe the changes of thyroid hormone of senile patients with chronic congestive heart failure (CHF) and to investigate the correlation between prognosis of the disease and serum thyroid hormone. Methods Serum FT 3, FT 4 and TSH in observation group and control group were measured by chemiluminescence enzyme immunoassay. Results FT 3 in observation group decreased significantly compared with that in control group (P<0.05). FT 4 reduced only in partial patients whose heart function class were IV, whereas their TSH were normal.Conclusion Thyroid hormone of senile patients with CHF was abnormal. The reduction of FT 3 and heart failure degree positive correlated and FT 3 could be the index for evaluating the state of the illness and prognosis of senile patients with CHF.
出处 《贵州医药》 CAS 2004年第10期882-883,共2页 Guizhou Medical Journal
关键词 患者 血清甲状腺激素 FT3 对照组 慢性充血性心力衰竭 CHF 老年 Thyroid hormone Heart failure Heart function
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  • 1Cinochowski CE, Harostock MD, Foldes PL. Minimal opertive mortality in patients undergoing coronary artery bypass with siginifcant left ventricular dysfunction by maximization of metabolic and mechanical support. J Thorac Cardiovasc surg, 1997,113: 655.
  • 2Kohon, Muradawak K,Yasunari K,et al. Circulating atrial natriuretic peptides in hyperthyroidism and hypothyroidism and hypothyroidism. Am J Med, 1987,87: 648.
  • 3Moruzzi P,Doria E, Agostini PG, et al.Usefulness of Lthyroxine to improve cardiac and exercise performance in idiopathic dilated cardiomyopathy. Am J cardiol, 1994,73: 374- 37.

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