摘要
本文对食管癌高发区15～26岁的青少年538例进行了流行病学调查,发现青少年中食管炎很常见,并对其中186例作了食管涂片微核细胞检测。186例中轻度或中度食管炎占2.7%.很轻度19.9%,正常组77.4%。三个组中微核率未见明显差别,且平均微核率在食管炎诊断及家族史、吸烟、口腔粘膜白斑、热饮及新鲜水果的摄入项中也未见差别。结果表明,如果将食管炎作为食管癌发展过程中的一个重要癌前状态,那么对于轻型食管炎微核检测不能作为一个有效的监测手段。
An epidemiologic survey among 538 young persons between 15～26 years of age in a high-risk area for esophageal cancer revealed a high prevalence of esophagitis.The prevalence of micronuclei in esophageal smears was assayed in a subsample.Of the 186 subjects,those with mild or moderate esophagitis accounted for 2.7%,those with very mild esophagitis for 19.9% and those normal for77.4 %.The frequent distribution of micronucleated cells in the esophageal mucosa was similar in the 3 diagnostic groups.Mean pereentages of micronucleated cells did not differ in the diagnosis of esophagitis,the household status,the current smoking status.the presence of oral leukoplakia and the consumption of burning hot beverages and of fresh fruit.The results suggest that,if esophagitis were considered an important precursor state in the development of esophageal cancer,the scoring of micronuclei would not appear to be an efficient test for mild forms of esophagitis.
出处
《河南肿瘤学杂志》
1993年第1期10-13,共4页
Henan Journal of Oncology
关键词
微核
食管炎
食管肿瘤
癌
micronucleus
esophagitis
esophageal cancer
