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动脉灌注丹参联合动脉化疗栓塞术治疗中心型肺癌的疗效分析 被引量:6

Arterial radix salviae miltiorrhizae infusion combined with chemoembolization in treating central pulmonary carcinoma
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摘要 目的 观察经动脉灌注丹参联合动脉化疗栓塞术治疗中心型肺癌的近期疗效。方法 对 13例中心型肺癌进行选择性支气管动脉、肋间动脉及胸廓内动脉造影 ,将 3F同轴微导管置于肿瘤的供血动脉内 ,灌注复方丹参注射液 16ml ,注入适当剂量的碘化油 顺铂乳剂。结果 肿瘤供血动脉以支气管动脉为主者 7例 ,以肋间动脉为主者 4例 ,以胸廓内动脉为主者 2例。治疗后临床症状改善率为 10 0 % ,且无严重并发症发生 ,1年生存率为 92 .3 1% (12 / 13 )。 Objective To explore the therapeutic effect of arterial radix salviae miltiorrhizae (RSM) infusion combined with chemoembolization in treating central pulmonary carcinoma. Methods Thirteen patients with central pulmonary carcinoma were diagnosed pathologically. Angiographic studies of the selective bronchial arteries, intercostal arteries and internal thoracic arteries were performed to provide for tumor dissection and arterial maps in all patients with primary lung carcinoma. A 3-F catheter was coaxially placed directed into the artery feeding the tumor, and 16 ml RSM was administered. Then iodized oil mixed with 100 mg Cisplatinum was injected under fluoroscopic control for embolization. Results Abnormal blood supplied arteries of central pulmonary carcinoma were found in 6 cases, 4 derived from intercostal arteries and 2 derived from internal thoracic arteries. After arterial RSM infusion combined with chemoembolization, alleviation of clinical symptoms was observed in all 13 cases (100%). No severe complications occurred. One-year survival rate was 92.31%(12/13). Conclusion Arterial RSM infusion combined with chemoembolization may be clinically effective for central pulmonary carcinoma.
出处 《中国医学影像技术》 CSCD 2004年第9期1418-1420,共3页 Chinese Journal of Medical Imaging Technology
关键词 肺肿瘤 丹参 动脉 栓塞 Pulmonary neoplasms Radix salviae miltiorrhizae Artery Chemoembolization
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  • 1Konno T. Targeting cancer chemotherapeutic agents by use of lipiodol contrast medium[J]. Cancer,1990,66(9):1897.
  • 2Najarian KE, Morris CS. Arterial embolization in the chest[J]. J Thorac Imaging,1998,13(2):93.
  • 3Zhang PT, Pei YX,Qi X, et al. Influence of blood-activating drugs on adhesion and invasion of cells in lung cancer patients[J]. Chinese Journal of Integrated Traditional and Western Medicine,1999,19(2):103-105.张培彤, 裴迎霞, 祁鑫,等. 活血药对人肺癌细胞黏

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