摘要
①目的 观察α D3 治疗婴幼儿维生素D缺乏性佝偻病的效果。②方法 选择维生素D缺乏性佝偻病病儿 78例 ,随机分为两组 ,α D3 组 4 0例 ,应用α D3 0 .12 5～ 0 .375 μg/d口服治疗 ,疗程 30d ;VitD3 组 38例 ,应用VitD3 15～ 2 0万单位行一次性肌肉注射治疗 ,观察两组病儿相关临床症状、血BALP变化、血清钙均值变化。③结果 两组病儿治疗前后相关临床症状、血BALP变化、血清钙磷均值变化差异均无显著意义 (χ2 =0 .0 3～ 0 .39,t=0 .2 8,P >0 .0 5 )。④结论 α D3 治疗维生素D缺乏性佝偻病效果可靠。
Objective To observe the effects of α-D 3 in the treatment of infantile vitamin D deficiency rickets. Methods Seventy-eight infants with vitamin D deficiency rickets were randomly divided into two groups, in which, 40 were treated with oral α-D 3 0.125-0.375 μg/d for 30 day, and 38 were treated with Vit D 3 150 000-300 000 U (single intramuscular injection). The changes of correlative clinical symptoms, serum bone alkaline phosphotase(BALP), and serum calcium were observed in both groups. Results The correlative clinical symptoms, serum BALP and calcium concentration were not significantly different between the groups(χ 2=0.03-0.39,t=0.28,P> 0.05). Conclusion α-D 3 is safe and reliable for the treatment of vitamin D deficiency rickets.
出处
《齐鲁医学杂志》
2004年第6期505-506,共2页
Medical Journal of Qilu
