2Elbashir SM , HarbortH,Lendackel, et al.Duplexes of 21-nucleotide RNAs medate RNA interference in cultured mammalian cells [J]. Nature,2000 , 411 : 494-498
3Giladi H ,Ketzinel-Gilad M ,Rivkin L,et al.Small interfering RNA inhibits hepatitis B virus replication in mice.[J].Molecular Therapy , 2003,8(5):769-776
4Klein C,Bock C,Wedemeyer H,et al.Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA [J].Gastroenterology,2003,125(l):9-18
5Kapadia SB , Brideau-Andersen A ,Chisari FV.Interference of hepatitis C virus RNA replication by short interfering RNAs [J].Proc Natl Acad Sci USA,2003,100(4):2014-2018
6Jacque JM ,Triques L,Stevenson M. Modulation of HIV-1 replication by RNA interference [J].Nature,2002,418:435-438
7Tuschl T .Zamore P.D, Lehmann R,et al.Targeted mRNA degradation by double-stranded RNA in vitro[J].Genes & Dev,1999,13: 3191-3197
8BemsteinE , Caudy AA , Hammond SM ,et al. Role for a bidentate ribonuclease in the initiation step of RNA interference [J].Natura,2001,409:363 -366
9Elbashir SM , LendeckelW,Tushl T.RNA interference is mediated by 21 -22-nucleotide RNAs [J].Gene Dev,2001,15:188-200
10Hammond SM, Bemsteine,BeachD,et al.An RNA-directed nuclease mediates post transcriptional gene silencing in Drosophila cells [J].Nature,2000 , 404 : 293-296
二级参考文献10
1Paul CP, Good PD, Winer I, et al. Effective expression of small interfering RNA in human cells. Nat Biotechnol,2002,20:505-508.
2Matzke M, Matzke AJ, Kooter JM. RNA: guiding gene silencing. Science, 2001, 293:1080-1083.
3Sui G, Soohoo C, Affar el B, et al. a DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA, 2002, 99: 5515-5520.
4Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in culture mammalian cells. Nature, 2001, 411: 494-498.
5Gitlin L, Karelsky S, Andino R . Short interfering RNA confers intracellular antiviral immunity in human cells. Nature, 2002, 418: 430-434.
6Lee NS, Dohjima T, Bauer G, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol, 2002, 20: 500-505.
7Jacque JM, Triques K, Stevenson M . Modulation of HIV-1 replication by RNA interference. Nature, 2002, 418: 435-438.
8Coburn GA, Cullen BR. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J Virol, 2001, 76: 9225-9231.
9Sprinzl MF, Oberwinkler H, Schaller H, et al. Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: crossing the species barrier. J Virol, 2001, 75:5108-5118.
10Tang H, McLachlan A. Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is critical determinant of viral tropism. Proc Natl Acad Sci USA, 2001, 98: 1841-1846.
