摘要
目的 探讨治疗严重眼烧伤后角巩膜溶解的有效方法。方法 对于Ⅳ度眼烧伤出现角巩膜溶解 ,经药物治疗未能控制的病例 ,在手术显微镜下操作 ,应用组织粘合剂联合羊膜移植手术进行治疗 11例。 结果 术后 11例患者中 5眼巩膜溶解均得到控制 ,表面发生纤维血管化 ;8例角膜上皮化愈合 ,3例角膜溃疡得到有效抑制。 结论 采用手术显微镜下进行组织粘合剂联合羊膜移植手术能有效阻止眼烧伤后的角巩膜溶解 ,维持眼球的完整性 ,为进一步的复明手术治疗创造良好的条件。
Objective To evaluate the strategy using cyanoacrylate tissue adhesive (CTA) in amniotic membrane transplantaton(AMT) to manage corneoscleral melting in severe ocular burns. Methods Twelve eyes from eleven patients with chemical or thermal burns of grade Ⅳ were recruited for this study.After medical treatment failed to arrest corneal or sclera melting,CTA were applied directly on the ulcerating corneal or sclera surface to augmented AMT. Results In all cases,all sclera ulcerations (five of eleven) were prevented or healed,epithelialization of burned cornea (eight of eleven) was complete,corneal ulceration in the rest three eyes was successfully arrested. Conclusion Tissue adhesive aided amniotic membrane transplantation is a promising altermnative in managing severe corneoscleral melting in chemical or thermal burns to maintain the integrity of the ocular wall.
出处
《中华显微外科杂志》
CSCD
北大核心
2004年第3期183-185,i003,共4页
Chinese Journal of Microsurgery
关键词
眼烧伤
角巩膜溶解
显微手术
手术治疗
羊膜移植
Cyanoacrylate tissue adhesive
Amniotic membrane
Transplantation
Ocular burns
Microsurgical operation
