摘要
目的比较抑郁发作、精神分裂症与神经症脑电波的特点。方法通过数字化脑电图记录各波功率值及总波功率值 ,对 3 0例抑郁发作、3 0例精神分裂症、3 0例神经症与 3 0例正常人的脑电波进行对照研究。采用受试者运筹曲线 (ROC)获取鉴别诊断的阈值。结果四组间的总波功率值和α波值存在显著性差异 ( P <0 .0 5 )。抑郁发作组总波功率值低于精神分裂症组 ( P <0 .0 1)及正常组 ( P <0 .0 5 ) ,θ波、α波和α波 /SMR波低于精神分裂症组 (P <0 .0 5 ) ,抑郁发作组还有α波低于神经症组 (P <0 .0 5 )及正常组 (P <0 .0 1)。θ波与α波合并值作为区别抑郁发作与精神分裂症两组患者的最佳截断值有 4个 :92 2 .5 3、994.67、10 66.3 8、1162 .84(灵敏度 46.7%～ 5 6.7% ,特异度 80 %～ 90 % )。结论总波功率值、θ波及α波可作为抑郁发作临床诊断参考指标 ,尤其α波降低意义更大。θ波与α波合并值 10 0 0可以作为临床鉴别是否为抑郁状态的参考阈值。
Objective To compare the characters of brainwave in depression, schizophrenia and neurosis. MethodsThe brainwave was measured in 30 patients with depression, 30 patients with schizophrenia, 30 patients with neurosis and 30 normal controls. The power of total EEG and each brainwave was recorded. The results of each group were compared. Receive Operating Curve was used to obtain the cut off value to distinguish clinical diagnosis. Results The power of total EEG and the value of alpha from the four groups were significantly different(P<0.05). The power of total EEG in the depression group were lower than that of the schizophrenia group (P<0.01) and the normal control group (P<0.05).theta, alpha and the ratio of alpha/ SMR in the depression group were lower than that of the schizophrenia group (P<0.05). The alpha of the depression group were lower than that of the neurosis group (P<0.05) and the normal control group (P<0.01). Four values of the theta plus the alpha (922.53、994.67、1066.38、1162.84) could be used as the cut off values to distinguish depression and schizophrenia (sensitivity 46.7%～56.7%,specificity 80%～90%)。ConclusionThe power of total EEG, the theta and the alpha could be served as a clinical reference index for the diagnosis of depression, which the lowness of the alpha was especially much meaningful. The value 1 000 of theta plus alpha could be a reference threshold to distinguish whether a patient was in a depressive state.
出处
《中国行为医学科学》
CSCD
2004年第5期522-523,共2页
Chinese Journal of Behavioral Medical Science
