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刘氏湿热清治疗温病湿热证的临床疗效观察及部分作用机理研究

Clinical Effect of Dr. Liu's ShiRe Qing on Dampness-heat Syndrome in Epidemic Febrile Diseases and A Preliminary Study of Its Mechanism
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摘要 本文观察了刘氏湿热清对25例温病湿热证的疗效,并设西药治疗作对照组,对两组患者的血液分析、血浆内毒素含量、红细胞免疫粘附功能等指标也进行了同步观察。结果表明:治疗组25例患者,治愈20例(80%)、显效2例(8%)、有效2例(8%)、无效1例(4%);对照组18例患者治愈13例(72.2%)、显效1例(5.6%)、有效2例(11.1%),无效2例(11.1%),两组疗效相当(P>0.05)。治疗后,湿热清组血浆内毒素含量比西药组明显降低(P<0.01),红细胞C_3b受体花环率明显升高,红细胞免疫复合物花环率明显下降(P<0.01)。上述结果提示刘氏温热清对温病湿热证有良好的治疗作用,其机理可能与其降低血浆内毒素水平,增强机体免疫功能有关。 In this study, the effects of Dr. Liu's ShiRe Qing on 25 cases of dampness-heat syndrome occurring in epidemic febrile disease were observed, with 18 cases receiving western medicine as control. The two groups were compared in terms of hematology, endotoxin content in plasma and RBC immunoad herence function. The overall effectiveness of two groups were 96% and 88.9% respectively, the difference being insignificant (P>0.05). But as compared with the control group, in the group receiving ShiRe Qing the plasma endotoxin content was significantly reduced (P<0.01) the RBC C_(3b)-receptor rosette rate significantly increased and the RBC immunocomplex rosette rate significantlyd decreased (P<0.01). It is indicated that Dr. Liu's ShiRe Qing is effective in the treatment of dampness-heat syndrome occurring in epidemic febrile diseases. Its mechanism may be related to the reduction of plasma endotoxin content and the enhancement of immune function.
出处 《广州中医学院学报》 1993年第4期191-194,共4页
关键词 湿热 中医药疗法 刘氏湿热清 免疫学 内毒素 DAMPNESS-HEAT(TCM)/TCM ther. @DR.LIU'S SHIRE QING/ther. use DAMPNESS-HEAT(TCM)/immunol. ENDOTOXINS/blood
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  • 1陈琼芳,周建年,周苏廉,张纪宁,胡有长,谢风香.庆大霉素对小鼠免疫的影响[J]中国病理生理杂志,1988(05).

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