摘要
目的 :探讨促性腺激素释放激素激动药曲普瑞林用于子宫内膜异位症保守性手术后辅助治疗的疗效和安全性。方法 :回顾分析 37例子宫内膜异位症患者保守性手术后的随访资料 ,比较应用曲普瑞林与未用药组的复发率 ,观察药物不良反应。结果 :观察组复发率 5 .5 % ,明显低于对照组复发率 (36 .8% ) ,P <0 .0 5。曲普瑞林不良反应主要为低雌激素引起的绝经期症状 ,停药后不良反应消失 ,不影响疗程 ,停药后 4～ 9周月经恢复。结论
Objective: To investigate the effects and safety of Triptorelin for treating patients with pelvic endometriosis after conservative operation.Method: 37 Postoperative pelvic endometriosis cases were analyzed retrospectively. Of these cases, 18 were administered Triptorelin (study group), other 19 cases hadn't taken any hormone drugs(control group). Recurrence rate was compared between two group, and the main side effects were recorded respectively.Result: The recurrence rate of study group was )5.5%), which was significantly lower than that of control group()36.8%)), P<)0.05). Hypoestrogenic effects occurred to study group who received Triptorelin, which can be alleviate after treatment.Menstruation recovered in all patients in 4-9 weeks after treatment.Conclusion: The treatment of Triptorelin on postoperative patients with pelvic endometriosis is effective and safe.
出处
《药物流行病学杂志》
CAS
2004年第4期180-182,共3页
Chinese Journal of Pharmacoepidemiology
