摘要
目的 探讨放射治疗配合DF方案化疗对食管癌治疗的价值。方法 将 14 4例食管癌患者随机分为 2组进行研究。综合组72例行放射治疗配合DF方案化疗 ,单放组 72例行单纯放射治疗。 2组随访均 3年。结果 综合组与单放组 1、2、3年生存率分别为 62 .5 %、45 .8%、3 4.7%和 44 .4%、3 1.9%、16.6% ,综合组 1、2、3年生存率明显高于单放组 (P <0 .0 5 ) ,且无严重毒副反应发生。 2组局控率差异无显著意义 (P >0 .0 5 ) ,远地转移率综合组低于单放组 (P <0 .0 5 )。结论 放射治疗食管癌配合DF方案化疗是疗效好、值得进一步研究的方法。
Objective To study the therapeutic effect of chemotherapy with DF regimen after radiotherapy for esophageal carcinoma,Methods A prospective randomized trial on chemotherapy was DF regimen after radiotherapy for esophageal carcinoma with carried out in 144 patients.The patients were randomized into combined group (R+C,72 patients)or radiotherapy alone group (R,72 patients).Both groups were followed up for 3 years.Results The one,two and three-year survival rates were 62.5%,45.8%,34.7% in R+C group and 44.4%,31.9%,16.6% in R group,respectively.The survival rates in R+C group were much better than those in R group (P<0.05).The local control rates,45.8% in R+C group and 52.7% in R group,had no difference (P>0.05).But there was significant differece in distant metastasis between the two groups.Conclusions chemotherapy with DF regimen after radiotherapy for esophageal carc inoma has good effect and is worth further studying in clinic.
出处
《河南肿瘤学杂志》
2004年第5期348-349,共2页
Henan Journal of Oncology
关键词
食管癌
化放疗
放疗
esophageal cancer
combined chemo-radiotherapy
radiotherapy.
