摘要
作者选用30只羊,随机分为实验组及对照组各15只。每只羊均行同侧股骨中段及胫骨中段截断造成横形骨折,股骨用梅花针、胫骨行斯氏针内固定。实验组口服左旋多巴,两组均于术后2、4、6、8、12周分别行X线检查、肉眼观察、组织学检查、扫描电镜检查和血液化学检查。结果表明实验组骨痂形成早、生长快、骨折愈合明显优于对照组。在此研究基础上将左旋多巴用于临床治疗骨折210例治疗结果优于对照组。文章讨论、分析了左旋多巴促进骨愈合的机理、临床应用价值及用药剂量与疗程。
Thirty local sheep were separated randomly into two groups experimental group and control group. Femoral bone and tibial bone of each sheep were divided transversally in the middle part. Femoral bone was fixed with in-tramedullary kuntscher nail and tibial bone was fixed with steinmann's pin. The experiment group took L-Dopa and was examined in the 2nd ,4th,6th,8th,and 12th week by X -ray .microscopic.histological.electro -microscope scanning and hemato-chemical examination.The result indicated that callus formed earlier and grew faster in experimental group than that of controll group. Authors adopted L-Dopa to treat 210 fracture cases on the basis of the experiment result. The therapeutic effect was satisfactory.
出处
《骨与关节损伤杂志》
1993年第3期178-181,共4页
The Journal of Bone and Joint Injury
