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重症病毒性脑炎患儿内环境紊乱的临床研究 被引量:28

A clinical study on internal milieu disorder in children with critical viral encephalitis
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摘要 目的 探讨重症病毒性脑炎 (VE)患儿应激性高血糖 (SHG)和电解质紊乱与病情发展的关系 ,并探索重症VE患儿血糖及血清钾、钠、钙的变化及其相互关系。方法 对 1999年 10月至 2 0 0 1年 5月吉林大学第一医院 5 8例重症VE患儿进行血糖及血清钾、钠、钙动态检测 ,并以 2 0例轻症VE患儿为对照组进行比较。结果 重症VE患儿易于发生SHG、低钠血症 (HN)、低钾血症 (HK )、低钙血症 (HC)。血糖的升高 ,血钠、血钙的降低与VE患儿病情轻重关系密切 ,随VE进入恢复期 ,存活者上述指标逐渐恢复正常。结论 重症VE患儿存在应激损伤 ,机体的过度应激反应亦可引起血清电解质的改变 ,由此加重内环境紊乱 ,故控制过度应激反应。 Objective To explore the relationship between irritable hyperglycemia and serum electrolyte on the development of illness in critical viral encephalitis children.Methods We detected dynamic changes of 4 indexes in 58 hospitalized pediatric patients who suffered from critical viral encephalitis.The detected items include blood glucose,serum K + ?Na + as well as blood calcium.Meanwhile a comparative analysis was done in 20 light viral encephalitis children as controls.Results Children who involved in critical viral encephalitis constantly showed hyperglycemia?hyponatremia?hypocalcemia and hypokalemia.It was noticed that there was a close correlation between hyperglycemia and the severity of diseases.These indexes were restored progressively when viral encephalitis turned for the better.Conclusion There really exist damage from stress in critical viral encephalitis children.Our results demonstrated that severe stress could make the serum electrolyte out of balance more serious .It must be beneficial for these patients to control excessive stress.
出处 《中国实用儿科杂志》 CSCD 北大核心 2004年第8期477-479,共3页 Chinese Journal of Practical Pediatrics
关键词 病毒性脑炎 应激性高血糖 血清钾 血清钠 血清钙 Viral encephalitis Irritable hyperglycemia Serum potassium Serum natrium Serurn calcium
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