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罗非昔布治疗膀胱手术后膀胱痉挛性疼痛的疗效观察

Rofecoxib in the treatment of bladder spasm in postoperative cycototmy and BPH patients
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摘要 目的 探讨罗非昔布治疗膀胱及前列腺手术后膀胱痉挛性疼痛的疗效。方法 将62例膀胱及前列腺手术后发作痉挛性疼痛者,按随机抽样法分为2组,第1组38例,口服罗非昔布25 mg,每日1~2次,共3 d;第2组30例作为对照组,口服丙胺太林(普鲁本辛)15 mg,3次·d-1,共3 d。结果 罗非昔布组治疗有效31/32(96.87%),对照组14/30(46.7%),经统计学检验有显著性意义(P<0.05)。结论 罗非昔布治疗膀胱术后发作痉挛性疼痛效果良好,作用确实。 OBJECTIVE To evaluate the clinical value of Rofecoxib in the treatment of bladder spasm in postopera-tivecycotomy and BPH patients. METHODS Sixty-two patients were divided into group A (32 patients) and group B (30 patients) . Group A received Rofecoxib 25 mg qd-bid and Group B received Pro-Banthine 15mg Tid for 3 days. RESULTS There was more significant therapeutic effect of celecoxib (96. 87%) than that of Pro-Banthine (46. 7%) (P<0. 05) . CONCLUSIONS: Rofecoxib is an effective drug in the treatment of bladder spasm in postoperative cy-cotomy and BPH patients.
出处 《中南药学》 CAS 2004年第4期246-247,共2页 Central South Pharmacy
关键词 罗非昔布 膀胱 手术后疼痛 Rofecoxib bladder spasm therapy
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  • 1HawkeyCJ.COX-2inhibitors[J].Lancet,1999,353∶307-314.
  • 2EhrichEW,DallobA,LepeleireID,etal.Characterizationofrofecoxibasacyclooxygenase-2isoforminhibitoranddemonstrationofanalgesiainthedentalmodel[J].ClinPharmacolTher,1999,65∶336-347.
  • 3MerckandCo.Inc.VioxxTMPrescribinginformation[R].NewJersey,USA.1998.
  • 4SaagK,FisherC,MckayJ,etal.MK-0966,aspecificCOX-2inhibitorshasclinicalefficacycomparabletoibuprofeninthetreatmentofkneeandhipOAinasix-weekcontrolledclinicaltrial[J].ArthritisRheum,1998,41(Suppl9)∶S84.
  • 5CannonG,CaldwellJ,HoltP,etal.MK-0966,aspecificCOX-2inhibitor,hasclinicalefficacycomparabletodiclofenacinthetreatmentofkneeandhipOAina26weekcontrolledclinicaltrial[J].ArthritisRheum,1998,41(Suppl9)∶S83.
  • 6MorrisonBW,DanielsSE,KoteyP,etal.Rofecoxib,aspecificcyclooxygenase-2inhibitor,inprimarydysmenorrhea:arandomizedcontrolledtrial[J].ObstetGynecol,1999,94(4)∶504-508.
  • 7SchwartzJI,ChanC,MukhopadhyayS,etal.Cyclooxygenase-2inhibitionbyrofecoxibreversesnaturallyoccurringfeverinhumans[J].ClinPharmacolTher,1999,65(6)∶653-660.
  • 8LanzaFL,SimonT,QuanH,etal.Selectiveinhibitionofcyclooxygenase-2withMK-0966(250mg,qd)isassociatedwithlessgastro-duodenaldamagethanaspirin(ASA)650mg,qidoribuprofen(IBU)800mg,tid[J].Gastroenterology,1997,112∶A194.
  • 9RynJV,PairetM.Clinicalexperiencewithcyclooxygenase-2inhibitors[J].InflammRes,1999,48∶247-254.
  • 10LaineL,HarperS,SimonT,etal.Arandomizedtrialcomparingtheeffectofrofecoxib,acyclooxygenase-2specificinhibitor,withthatofibuprofenonthegastroduodenalmucosaofpatientswithosteoarthritis[J].Gastroenterology,1999,117(4)∶776-783.

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