摘要
目的 :研究防茄软膏抗炎、镇痛的药效学。方法 :采用二甲苯对小鼠所至耳廓肿胀法 ,蛋清后跖肿胀法 ,热板法及大鼠棉球肉芽肿法等进行抗炎、镇痛试验。结果 :小鼠耳廓肿胀法与赋形剂组相比 ,抗炎差异有显著性 (P <0 .0 5 ) ,大鼠后足跖肿胀法与赋形剂组相比 ,抗炎差异具极显著性 (P <0 .0 1 ) ,大鼠棉球肉芽肿法与赋形剂组相比 ,差异具极显著性 (P <0 .0 1 ) ,热板法镇痛与赋形剂组相比 ,镇痛效果显著 (P <0 .0 1 )。结论 :防茄软膏具有一定的抗炎镇痛作用 ,具有深入研究价值。
OBJECTIVE To study the anti-inflammatory and pain-relieving effect of Fangjia ointiment. METHODS Swollen auricle of mice induced by xylene, swollen back-metatarsal rats induced by egg-white, heated plate and tampon granuloma in rats were employed to study the anti-inflammatory and pain-relieving of Fangjia ointment. RESULTS The difference of effect between Fangjia ointment group and the control group were extreme significant(P< 0.01) both in swollen back-metatarsal of rats and tampon granuloma tests, while in mice swollen auricle tests and heated plate tests, the difference were also significant(P< 0.05). CONCLUSION The anti-inflammatory and pain-relieving effects of Fangjia ointment were promising and valuable to be studied further.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2004年第5期283-284,共2页
Chinese Journal of Hospital Pharmacy
关键词
防茄软膏
抗炎
镇痛
Fangjia ointment
anti-inflammation
pain-reliecing
