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高压氧治疗急性一氧化碳中毒迟发性脑病的疗效观察 被引量:5

Observation of Hyperbaric Oxygen Therapy's Effects on Delayed Encephalopathy after Acute Carbon Monoxide Poisoning
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摘要 目的 探讨高压氧治疗急性一氧化碳 (CO)中毒后迟发性脑病的疗效。方法 对 76例并发迟发性脑病患者随机分为对照组 2 6例 ,采用常规综合治疗 ,观察组 5 0例 ,在常规治疗基础上加用高压氧治疗 ,治疗 4个疗程后评价其疗效。结果 观察组痊愈 3 9例 ( 78 0 %) ,有效率94.0 %,对照组痊愈 16例 ( 61.5 %) ,有效率 76 9%,观察组有效率明显高于对照组 (P <0 .0 5 ) ,治愈时间较对照组缩短 ,有显著性差异 (P <0 .0 5 )。结论 高压氧联合常规综合治疗 ,可提高CO中毒后迟发性脑病的近期疗效 ,缩短病程 。 Objective To discuss the curative effects of hyperbaric oxygenation in delayed encephalopathy after acute carbon monoxide poisoning.Methods 76 patients were divided randomly into control group(26) with routine combining therapy and experimental group(50) with hyperbaric oxygen therapy based on routine treatment.And then to evaluate the effects after 4 courses of treatment.Results The cure rate and the effective rate were 78% and 94% in experimental group,61.5% and 76.9% in control group.In experimental group,the effective rate was obviously higher and the cure time was shorter.There was a significant difference in statistics ( P <0.05).Conclusion Hyperbaric oxygen associated with routine combining therapy could raise curative effects in the near future,shorten the course of disease and improve the prognosis.
机构地区 解放军第
出处 《临床军医杂志》 CAS 2004年第3期9-10,共2页 Clinical Journal of Medical Officers
关键词 一氧化碳中毒 迟发性脑病 高压氧 carbon monoxide poisoning delayed encephalopathy hyperbaric oxygen
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  • 1[1]Walker E,Hay A.Carbon monoxide poisoning[J].B M J,1999,319:1082-1083.
  • 2[2]Ernst A,Zibrak J D.Carbon monoxide poisoning[J].New Engl J Med,1998,339(22):1603-1608.
  • 3[3]Thom S R,Fisher D,Xu Ya,et al.Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat[J].Am J Physiocal,1999,276(3):H984-H992.
  • 4李温仁,倪国坛.实用高压氧学.上海:上海科学技术出版社,1998:87-89.

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